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doi: 10.1111/j.1365-2982.2011.01796.x 18 BlackA

LA also shares structural similarities to the Vibrio cholerae zonula occludens toxin (Zot), which is an enterotoxin that disrupts intercellular tight junction structure through actin polymerization and cytoskeletal modifications that result in increased intestinal permeability through intracellular signaling (8)

Targeted liquid chromatography/mass spectrometry (LC/MS) analysis showed that glutathione levels were not only significantly reduced in NTG, but also in POAG (Fig

The next day, cells were embedded in Epon (Sigma-Aldrich, Buchs, Switzerland) and left to harden at 60 C for 5 days